Next batch of compounds sent for testing June 2021

[kym834]

In 2020, students at The University of Sydney synthesised six Series 4 compounds which have been tested for activity. Three (four including control compound OSM-S-293 which was resynthesised) showed activities at >1uM.

MMV Number	SMILE	InChI	InChI Key
MMV663915	ClC1=CC=C(C=C1)C2=NN=C3C=NC=C(N23)OCCC4=CC=CC=C4	InChI=1S/C19H15ClN4O/c20-16-8-6-15(7-9-16)19-23-22-17-12-21-13-18(24(17)19)25-11-10-14-4-2-1-3-5-14/h1-9,12-13H,10-11H2	VURCFSOLNXCMTN-UHFFFAOYSA-N
MMV664055	ClC1=CC=C(C2=NN=C3N2C(OCCC4=CC=C(OC)C=C4)=CN=C3)C=C1	InChI=1S/C20H17ClN4O2/c1-26-17-8-2-14(3-9-17)10-11-27-19-13-22-12-18-23-24-20(25(18)19)15-4-6-16(21)7-5-15/h2-9,12-13H,10-11H2,1H3	ZDIRIXBCGDRONA-UHFFFAOYSA-N
MMV1901011	ClC1=CC=C(C2=NN=C3N2C(OCCC4=CC(F)=CC=C4)=CN=C3)C=C1	InChI=1S/C19H14ClFN4O/c20-15-6-4-14(5-7-15)19-24-23-17-11-22-12-18(25(17)19)26-9-8-13-2-1-3-16(21)10-13/h1-7,10-12H,8-9H2	IMWFISQOVPAQSH-UHFFFAOYSA-N
MMV1901012	ClC1=CC=C(C2=NN=C3N2C(OCCC4=CC=C(F)C=C4)=CN=C3)C=C1	InChI=1S/C19H14ClFN4O/c20-15-5-3-14(4-6-15)19-24-23-17-11-22-12-18(25(17)19)26-10-9-13-1-7-16(21)8-2-13/h1-8,11-12H,9-10H2	XVAUKWCYBQWUDV-UHFFFAOYSA-N
MMV1901013	ClC1=CC=C(C2=NN=C3C=NC=C(N23)OCCC4=CC=CC=N4)C=C1	InChI=1S/C18H14ClN5O/c19-14-6-4-13(5-7-14)18-23-22-16-11-20-12-17(24(16)18)25-10-8-15-3-1-2-9-21-15/h1-7,9,11-12H,8,10H2	OQQNRJBXDGBECZ-UHFFFAOYSA-N
MMV1901014	ClC1=CC=C(C2=NN=C3N2C(OCCC4=CC=CC=C4Cl)=CN=C3)C=C1	InChI=1S/C19H14Cl2N4O/c20-15-7-5-14(6-8-15)19-24-23-17-11-22-12-18(25(17)19)26-10-9-13-3-1-2-4-16(13)21/h1-8,11-12H,9-10H2	MYTSEBRKFNBDNO-UHFFFAOYSA-N