diff --git a/packages/mui-material/src/Chip/Chip.js b/packages/mui-material/src/Chip/Chip.js
index 1bc38ef84f2531..3e576f5e3f37ae 100644
--- a/packages/mui-material/src/Chip/Chip.js
+++ b/packages/mui-material/src/Chip/Chip.js
@@ -461,9 +461,14 @@ const Chip = React.forwardRef(function Chip(inProps, ref) {
         React.cloneElement(deleteIconProp, {
           className: clsx(deleteIconProp.props.className, classes.deleteIcon),
           onClick: handleDeleteIconClick,
+          'aria-label': `Delete ${label || 'item'}`,
         })
       ) : (
-        <CancelIcon className={classes.deleteIcon} onClick={handleDeleteIconClick} />
+        <CancelIcon
+          className={classes.deleteIcon}
+          onClick={handleDeleteIconClick}
+          aria-label={`Delete ${label || 'item'}`}
+        />
       );
   }